Department of Biology

Biology 202 (001) Course Website
 

Molecular Biology and Genetics
Summer Session I. 2009

Dr. Kelly Hogan and Dr. Brian Hogan

  

Lectures:  107 Wilson Hall (Mon-Fri 9:45-11:15 AM)

 

Recitations:  (you should be registered for one of the 3 sections. Each section meets on Mondays, Wednesdays, and Fridays room locations TBA)

(Section 601: 12 PM, Section 602: 1 PM, Section 603: 12 PM)

 

Instructors:       Dr. Kelly Hogan                

                           Email: Kelly_Hogan@unc.edu

                        Office location: Wilson Hall 104B

                        Office phone: 843-6047

                        Office Hours: after class

                       

                           Dr. Brian Hogan

                           Email:hoganb@email.unc.edu

                           Office location: 203 Morehead Labs

                           Phone: 962-4746

                           Office hours: TBA  

Teaching Assistants: Jennifer Cable (jcable@email.unc.edu); sections 601 and 602

                                    Shara Reihani (sreihani@aol.com); section 603

 

COURSE WEBSITE: http://blackboard.unc.edu/ (you will need your onyen to log on)

This site will have postings from our lectures such as outlines, power point slides and supplemental material we mention in lecture. We will also post announcements on this site. It is your responsibility to check it regularly.     

                   

Introduction to Genetic Analysis, 9th Edition, W.H. Freeman & Co.

by Griffiths, Wessler, Lewontin, and Carroll

Chapter 1 will not be assigned reading, but it is a good overview. Read through it at the beginning of the course…and use it as a great review at the end of the course.

 

Use the website associated with the book! Web-based bioinformatics tutorials, animations, and other supplemental information can be found at http://bcs.whfreeman.com/iga9e/

 

Required e-instruction remote: Every student should purchase a remote (“clicker”) and register this remote through our class site at: blackboard.unc.edu (under “course tools”)

This clicker should be brought to every class. Use of the clicker is a component of the final grade (see below). *Note: the batteries can run out fast if used a lot…get a spare to keep with you. This is part of the responsibility of having a clicker.

 


 

Course Policies:

 

1.  Examination format:

Three semester exams and one final exam will be given.  The final examination is cumulative for the entire semester. Students are expected to take all exams and the final examination on the dates indicated during the regular class period. If an exam is missed due only to extenuating circumstances, i.e., medical or family emergency documented in writing, the points from that exam will be assigned to the other exams.

 

 

2.  Recitation:

Attendance and participation in the recitation section is a critical component of this course and, therefore, is required.  Recitation assignments correspond to the topics covered in lecture.  Students are expected to work the assignments prior to recitation.  Recitation will include in-class discussion of assignments and review.

Your recitation grade will consist of participation in class recitation quizzes (no make-ups given on these quizzes).

DON’T FALL BEHIND!

 

3.  Grading:

3 exams worth 20% each

cumulative final examination worth 25%

clicker grade worth 5%

recitation—10%  (includes required attendance/participation and quizzes)

 

Answers to problems on the exams will be posted after each exam, except for the final. Students must consult the key before contacting the instructor regarding grading questions. All requests for a re-grade must be handed in to the TA IN WRITING. The ONLY exception will be simple errors in addition.

 


 

Goals/Objectives of the Course:

1) You will learn to think beyond memorization by using higher order thinking skills to solve genetic/molecular biology problems given to you inside and outside of class. This is not high school; we know any UNC Chapel Hill student can recall information! Let’s not Blooms Taxonomy Diagram

only acquire knowledge but be able to use this knowledge in different ways (such as through application and analysis). This is the beginning of thinking like a scientist. You will have plenty of practice in lecture, recitation, and homework to hone these higher thinking skills. These problem sets will be the basis for exams too.

 

2) Despite not having a lab, you will think about laboratory techniques and practice scientific techniques on paper. For example: 1) you should be able to theoretically set up the proper genetic crosses to determine inheritance patterns of certain genes or 2) digest a plasmid and run DNA electrophoresis.
*Readings: use the skeleton notes and what we talk about in class to guide you. If a topic in the book is not discussed in lecture, then you will not be tested on it.

 


 

Lecture

Topic

Readings (chapter)

 

Tues May 12

Introduction to course & Structure of Genes and Genomes; Review of Meiosis

2.1, 2.2

KH

Wed May 13

Single Gene Inheritance and Pedigrees

2.2- 2.6

KH

Thurs May 14

Pedigrees and Independent Assortment

2.6 and 3.1-3.3

KH

Fri May 15

Genetic Recombination: Recombination, Linkage, Mapping

4.1 and 4.2

KH

Mon May 18

Finish recombination and begin Gene Interactions

4.1 and 4.2, 6.1

KH

Tues May 19

Gene Interactions continued

6.1-6.4

KH

Wed May 20

The Nature of DNA and DNA Replication

7.1-7.6

BH

Thurs May 21

Exam I (all material from May 12- May 19)

 

KH

Fri May 22

Gene Mutation and DNA Repair Mechanisms

Ch 15.1-15.5

 

BH

Mon May 25

Memorial Day Holiday- No class

 

 

Tues May 26

RNA: Transcription and Processing

8.1-8.4

BH

Wed May 27

Translation and Protein Structure and Function

9.1-9.6

BH

Thurs May 28

Genetics of bacteria and their viruses-part 1

Ch. 5

Sections 5.1-5.2

BH

Friday May 29

Genetics of bacteria and their viruses-part 2

Ch. 5

Sections 5.1-5.2

BH

Mon June 1

Exam 2 (all material from May 20-May 28)

 

BH

Tues June 2

Regulation of Prokaryotic Transcription

Ch. 10

Sections 10.1-10.2

BH

    Wed June 3

Regulation of Prokaryotic Transcription CONTINUED

Ch. 10

Sections 10.1-10.2

BH

Thur June 4

Recombinant DNA Technology

Ch. 20.1-20.2 plus info from notes

BH

Fri June 5

Recombinant DNA Technology

Ch. 20.1-20.2 plus info from notes

BH

Mon June 8

Chromosomes

Chapter 16

KH

Tues June 9

Exam 3 (material from May 29- June 5)

 

BH

Wed June 10

Stem Cells

 

Pdf files posted on Blackboard

KH

Thurs June 11

Modeling Human Disease in Mice

p. 745-753 and pdf

KH

Friday June 12

Forensics

p 151-3, 728, 731-5

KH

Monday  June 15

CUMULATIVE Final Exam

8-11 AM

BH

 

 

 

 

 

  


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